Sections

Personalized Medicine: Real Opportunities And Real Challenges For Doctors

Greg McStravick

In the first of a three-part series on how technology is transforming healthcare, Greg McStravick, GM and global head, SAP Platform GTM, takes a look at the potential of personalized medicine. Technology has the potential to create real value, but short-term challenges are significant. Find out more about technology and healthcare challenges and opportunities in Parts 2 and 3:

  • Part 2: Personalized Medicine and Big Data–Opportunities and Pitfalls of IT Innovation
  • Part 3: The Risks, Challenges–and Rewards–of Ensuring Medical Data Privacy

As we observe National Heart Month (#NationalHeartMonth) this February, it is both encouraging and exciting that a new effort is underway to create tailor-made medicine and medical treatments by drawing on exceptionally detailed and extensive biomedical data. The effort is ambitious and challengingand possible. The goal: wide availability of personalized medical care (aka precision medicine) that can be customized based on an individual’s genetic makeup and other factors.

But collecting this level of personal health care information, while it holds the possibility of game-changing personalized drugs and treatments, is not without major challenges–including those in the realms of patient privacy and data storage. Highly individualized diagnosis and treatment available on a large scale requires collection and management of petabytes of data, including but not limited to patient histories, genetic data, data from wearable health monitors, and information on individual microbiomes (bacteria, fungi, and viruses in and on the body). Privacy is of utmost concern, and even current big data standards could be strained by massive amounts of genetic data.

The possibilities are compelling, and the upside is huge. But personalized medicine is a challenge with real, difficult, and perhaps intractable problems attached.

Are we there yet?

We’ve been able to sequence the human genome for about 15 years. In certain specialties, such as oncology, we’re already seeing tremendous advancements thanks to genometrics. Cancer used to be thought of in terms of a cell gone wrong that affected the tissue around it, with treatments based on affected area – for example, lung, breast, or skin. Now, researchers are looking to treat each mutation by responding to its genetic fingerprint. The same treatment might be applicable regardless of the organ or tissue affected, and, for example, one patient’s lung cancer treatment might differ from another’s due to genetic differences in each person’s mutation.

However, along with important breakthroughs and new therapies to treat formerly untreatable diseases, we’ve also seen the need for exponentially more complex understanding – from not just researchers but front-line doctors. Now that we can sequence the DNA, we must understand and transcribe epigenomes, proteomes, metabolomes, and more. This poses a huge challenge for on-the-ground medical personnel, including primary care providers and specialists whose focus is broadly defined quality care.

Friend or foe?

The majority of physicians believe that personalized medicine will eventually create real value for individuals as well as entire populations. But in the short term, what will the average family practitioner get for her efforts? Physicians are under stress, working more and seeing patients less. Many doctors have just completed mandatory transitions to electronic medical records (EMRs), which has required more work but yielded little in tangible results. Privacy laws, insurance paperwork, and the shift to value-based pricing are requiring more data input and creating more hoops to jump through, lengthening the workday but providing minimal tangible value for patients and doctors. The fear here is that personalized medicine could mean more of the same for the vast majority of providers. Would primary care doctors need to verify even more information when a person is sick, taking into account all the additional characteristics that drive a doctor toward different therapies? Will all the new inputs yield equivalent benefits?

Outside the office

I believe that in order for personalized medicine to take off, we’ll need to capture not just genomic information, but accurate information about individual patients that falls well outside current hospital or clinical settings. How do patients live in their homes? What do they eat, drink, and smoke? What’s their documented level of physical and social activity? And even more important, how do we engage patients, especially those with chronic illness, in ways that support real change of unhealthy habits? I believe that for personalized medicine to reach its full preventative potential, the medical profession will have to engage with patients in their homes.

Also, correlating such lifestyle data is critically important to understanding and applying genomic data when predicting risk factors for certain diseases. But how will this lifestyle data be captured and stored? What infrastructure will be needed, and how will it be funded? Before we can consistently, accurately, and cost-effectively collect this data, we need a technology infrastructure and payment model in place.

Best practices: A final challenge

It can be a major challenge for the medical profession to implement best practices. Even when best practices are proven in controlled, randomized trials, it has often taken up to 20 years for a practice to be consistently adopted. Given this challenge, for personalized medicine protocols to really work for–and be consistently adopted by–doctors, they must:

  • Be time-neutral
  • Integrate into current workflows
  • Drive clear value for both doctors and their patients

It’s only when we address all these challenges–both technological and human-based–that we will be able to truly take advantage of the benefits that personalized medicine can offer.

Learn more about the SAP Foundation for Health and Personalized Medicine

SAP is passionate about creating transformative technology that can advance healthcare. The SAP Foundation for Health includes a sophisticated platform and advanced analytic solutions that can help unlock the value of biomedical data–from genomes to electronic medical records to clinical trials. Supporting deeper insights and enabling collaboration, the SAP Foundation for Health helps connect data silos and bring together mission-critical biomedical data, advancing personalized medicine to new levels.

Visit SAP at #HIMSS16 Booth #5828 February 29-March 4 to learn more, or continue the discussion on Twitter @SAP_Healthcare.

 

 

Comments

Greg McStravick

About Greg McStravick

Greg McStravick is the President of Database and Data Management at SAP, leading development and go-to-market teams for SAP’s core digital innovation platform, SAP HANA and Sybase databases (including ASE, and IQ), enterprise information management, middleware, and SAP HANA Vora. Formerly, Greg led the go-to-market teams and strategy for some of SAP’s largest and fastest growing businesses including the SAP HANA platform, analytics, database, and SAP HANA Cloud Platform. With more than 20 years of progressive experience as a leader in technology solution sales management and strategy, Greg has held senior leadership positions throughout SAP, including President (U.S.), where he was responsible for driving customer success and developing new opportunities for SAP to expand its business across the entire U.S. region.

IoT Can Keep You Healthy — Even When You Sleep [VIDEO]

Christine Donato

Today the Internet of Things is revamping technology. IoT image from American Geniuses.jpg

Smart devices speak to each other and work together to provide the end user with a better product experience.

Coinciding with this change in technology is a change in people. We’ve transitioned from a world of people who love processed foods and french fries to people who eat kale chips and Greek yogurt…and actually like it.

People are taking ownership of their well-being, and preventative care is at the forefront of focus for both physicians and patients. Fitness trackers alert wearers of the exact number of calories burned from walking a certain number of steps. Mobile apps calculate our perfect nutritional balance. And even while we sleep, people are realizing that it’s important to monitor vitals.

According to research conducted at Harvard University, proper sleep patterns bolster healthy side effects such as improved immune function, a faster metabolism, preserved memory, and reduced stress and depression.

Conversely, the Harvard study determined that lack of sleep can negatively affect judgement, mood, and the ability retain information, as well as increase the risk of obesity, diabetes, cardiovascular disease, and even premature death.

Through the Internet of Things, researchers can now explore sleep patterns without the usual sleep labs and movement-restricting electrode wires. And with connected devices, individuals can now easily monitor and positively influence their own health.

EarlySense, a startup credited with the creation of continuous patient monitoring solutions focused on early detection of patient deterioration, mid-sleep falls, and pressure ulcers, began with a mission to prevent premature and preventable deaths.

Without constant monitoring, patients with unexpected clinical deterioration may be accidentally neglected, and their conditions can easily escalate into emergency situations.

Motivated by many instances of patients who died from preventable post-elective surgery complications, EarlySense founders created a product that constantly monitors patients when hospital nurses can’t, alerting the main nurse station when a patient leaves his or her bed and could potentially fall, or when a patient’s vital signs drop or rise unexpectedly.

Now EarlySense technology has expanded outside of the hospital realm. The EarlySense wellness sensor, a device connected via the Internet of Things, mobile solutions, and supported by SAP HANA Cloud Platform, monitors all vital signs while a person sleeps. The device is completely wireless and lies subtly underneath one’s mattress. The sensor collects all mechanical vibrations that the patient’s body emits while sleeping, continuously monitoring heart and respiratory rates.

Watch this short video to learn more about how the EarlySense wellness sensor works:

The result is faster diagnoses with better treatments and outcomes. Sleep issues can be identified and addressed; individuals can use the data collected to make adjustments in diet or exercise habits; and those on heavy pain medications can monitor the way their bodies react to the medication. In addition, physicians can use the data collected from the sensor to identify patient health problems before they escalate into an emergency situation.

Connected care is opening the door for a new way to practice health. Through connected care apps that link people with their doctors, fitness trackers that measure daily activity, and sensors like the EarlySense wellness sensor, today’s technology enables people and physicians to work together to prevent sickness and accidents before they occur. Technology is forever changing the way we live, and in turn we are living longer, healthier lives.

To learn how SAP HANA Cloud Platform can affect your business, visit It&Me.

For more stories, join me on Twitter.

Comments

Christine Donato

About Christine Donato

Christine Donato is a Senior Integrated Marketing Specialist at SAP. She is an accomplished project manager and leader of multiple marketing and sales enablement campaigns and events, that supported a multi million euro business.

Zhena’s Gypsy Tea Brews Sustainable Growth On Cloud ERP

David Trites

Recently I had the pleasure of hosting a podcast with Paula Muesse, COO and CFO of Zhena’s Gypsy Tea, a small, organic, fair-trade tea company based in California, and Ursula Ringham from SAP. We talked about some of the business challenges Zhena’s faces and how the company’s ERP solution helped spur growth and digital transformation.

Small but complex business

~ERP helped Zhena’s sustain growthZhena’s has grown from one person (Zhena Muzyka) selling hand-packed tea from a cart, into a thriving small business that puts quality, sustainability, and fair trade first. And although the company is small its business is complex.

For starters, tea isn’t grown in the United States, so Zhena’s has to maintain and import inventory from multiple warehouses around the world. Some of their tea blends have up to 14 ingredients, and each one has a different lead time. That makes demand-planning difficult. In addition, the FDA and US Customs require designated ingredients be traced and treated a certain way to comply with regulations.

Being organic and fair trade also makes things more complicated. Zhena’s has to pass an annual organic compliance audit for all products and processing facilities. And all products need to be traceable back to the farms where the tea was grown and picked to ensure the workers (mostly women) are paid fair wages.

Sustainable growth

Prior to implementing its new ERP system, Zhena’s was using a mix of tools like QuickBooks, Excel, and paper to manage the business. But to sustain growth and ensure future success, the company had to make some changes. Zhena’s needed an integrated software solution that could handle all facets of the business. It needed a tool that could help with cost control and profitability analysis and facilitate complex reporting and regulatory requirements.

The SAP Business ByDesign solution was the perfect choice. The cloud-based ERP solution reduced both business and IT costs, simplified processes from demand planning to accounting, and enabled mobile access and real-time reporting.

Check out the podcast to hear more about how Zhena’s successfully transformed its business by moving to SAP Business ByDesign.

 This article originally appeared on SAP Business Trends.

Building a successful company is hard work. SAP’s affordable solutions for small and midsize companies are designed to make it easier. Simple to install and use, SAP SME Solutions help you automate and integrate your business processes to give real-time, actionable insights. So you can make decisions on the spot. Find out how Run Simple can work for you. Visit sap.com/sme.

Comments

David Trites

About David Trites

David Trites is a Director of SAP Global Marketing. He is responsible for producing interesting and compelling customer stories that will humanize the SAP brand, support sales and marketing teams across SAP, and increase the awareness of SAP in key markets.

How Emotionally Aware Computing Can Bring Happiness to Your Organization

Christopher Koch


Do you feel me?

Just as once-novel voice recognition technology is now a ubiquitous part of human–machine relationships, so too could mood recognition technology (aka “affective computing”) soon pervade digital interactions.

Through the application of machine learning, Big Data inputs, image recognition, sensors, and in some cases robotics, artificially intelligent systems hunt for affective clues: widened eyes, quickened speech, and crossed arms, as well as heart rate or skin changes.




Emotions are big business

The global affective computing market is estimated to grow from just over US$9.3 billion a year in 2015 to more than $42.5 billion by 2020.

Source: “Affective Computing Market 2015 – Technology, Software, Hardware, Vertical, & Regional Forecasts to 2020 for the $42 Billion Industry” (Research and Markets, 2015)

Customer experience is the sweet spot

Forrester found that emotion was the number-one factor in determining customer loyalty in 17 out of the 18 industries it surveyed – far more important than the ease or effectiveness of customers’ interactions with a company.


Source: “You Can’t Afford to Overlook Your Customers’ Emotional Experience” (Forrester, 2015)


Humana gets an emotional clue

Source: “Artificial Intelligence Helps Humana Avoid Call Center Meltdowns” (The Wall Street Journal, October 27, 2016)

Insurer Humana uses artificial intelligence software that can detect conversational cues to guide call-center workers through difficult customer calls. The system recognizes that a steady rise in the pitch of a customer’s voice or instances of agent and customer talking over one another are causes for concern.

The system has led to hard results: Humana says it has seen an 28% improvement in customer satisfaction, a 63% improvement in agent engagement, and a 6% improvement in first-contact resolution.


Spread happiness across the organization

Source: “Happiness and Productivity” (University of Warwick, February 10, 2014)

Employers could monitor employee moods to make organizational adjustments that increase productivity, effectiveness, and satisfaction. Happy employees are around 12% more productive.




Walking on emotional eggshells

Whether customers and employees will be comfortable having their emotions logged and broadcast by companies is an open question. Customers may find some uses of affective computing creepy or, worse, predatory. Be sure to get their permission.


Other limiting factors

The availability of the data required to infer a person’s emotional state is still limited. Further, it can be difficult to capture all the physical cues that may be relevant to an interaction, such as facial expression, tone of voice, or posture.



Get a head start


Discover the data

Companies should determine what inferences about mental states they want the system to make and how accurately those inferences can be made using the inputs available.


Work with IT

Involve IT and engineering groups to figure out the challenges of integrating with existing systems for collecting, assimilating, and analyzing large volumes of emotional data.


Consider the complexity

Some emotions may be more difficult to discern or respond to. Context is also key. An emotionally aware machine would need to respond differently to frustration in a user in an educational setting than to frustration in a user in a vehicle.

 


 

download arrowTo learn more about how affective computing can help your organization, read the feature story Empathy: The Killer App for Artificial Intelligence.


Comments

Christopher Koch

About Christopher Koch

Christopher Koch is the Editorial Director of the SAP Center for Business Insight. He is an experienced publishing professional, researcher, editor, and writer in business, technology, and B2B marketing. Share your thoughts with Chris on Twitter @Ckochster.

Tags:

In An Agile Environment, Revenue Models Are Flexible Too

Todd Wasserman

In 2012, Dollar Shave Club burst on the scene with a cheeky viral video that won praise for its creativity and marketing acumen. Less heralded at the time was the startup’s pricing model, which swapped traditional retail for subscriptions.

For as low as $1 a month (for five two-bladed cartridges), consumers got a package in the mail that saved them a trip to the pharmacy or grocery store. Dollar Shave Club received the ultimate vindication for the idea in 2016 when Unilever purchased the company for $1 billion.

As that example shows, new technology creates the possibility for new pricing models that can disrupt existing industries. The same phenomenon has occurred in software, in which the cloud and Web-based interfaces have ushered in Software as a Service (SaaS), which charges users on a monthly basis, like a utility, instead of the typical purchase-and-later-upgrade model.

Pricing, in other words, is a variable that can be used to disrupt industries. Other options include usage-based pricing and freemium.

Products as services, services as products

There are basically two ways that businesses can use pricing to disrupt the status quo: Turn products into services and turn services into products. Dollar Shave Club and SaaS are two examples of turning products into services.

Others include Amazon’s Dash, a bare-bones Internet of Things device that lets consumers reorder items ranging from Campbell’s Soup to Play-Doh. Another example is Rent the Runway, which rents high-end fashion items for a weekend rather than selling the items. Trunk Club offers a twist on this by sending items picked out by a stylist to users every month. Users pay for what they want and send back the rest.

The other option is productizing a service. Restaurant franchising is based on this model. While the restaurant offers food service to consumers, for entrepreneurs the franchise offers guidance and brand equity that can be condensed into a product format. For instance, a global HR firm called Littler has productized its offerings with Littler CaseSmart-Charges, which is designed for in-house attorneys and features software, project management tools, and access to flextime attorneys.

As that example shows, technology offers opportunities to try new revenue models. Another example is APIs, which have become a large source of revenue for companies. The monetization of APIs is often viewed as a side business that encompasses a wholly different pricing model that’s often engineered to create huge user bases with volume discounts.

Not a new idea

Though technology has opened up new vistas for businesses seeking alternate pricing models, Rajkumar Venkatesan, a marketing professor at University of Virginia’s Darden School of Business, points out that this isn’t necessarily a new idea. For instance, King Gillette made his fortune in the early part of the 20th Century by realizing that a cheap shaving device would pave the way for a recurring revenue stream via replacement razor blades.

“The new variation was the Keurig,” said Venkatesan, referring to the coffee machine that relies on replaceable cartridges. “It has started becoming more prevalent in the last 10 years, but the fundamental model has been there.” For businesses, this can be an attractive model not only for the recurring revenue but also for the ability to cross-sell new goods to existing customers, Venkatesan said.

Another benefit to a subscription model is that it can also supply first-party data that companies can use to better understand and market to their customers. Some believe that Dollar Shave Club’s close relationship with its young male user base was one reason for Unilever’s purchase, for instance. In such a cut-throat market, such relationships can fetch a high price.

To learn more about how you can monetize disruption, watch this video overview of the new SAP Hybris Revenue Cloud.

Comments